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Enzymes ( Digestive Enzymes)

What is it? (physiology and clinical effects)
Enzymes are proteins that are involved in nearly all bodily functions. There are two groups of enzymes: metabolic enzymes and digestive enzymes. Metabolic enzymes help in processes such as energy production and detoxification in all the body's organs, tissues, and cells. Digestive enzymes help break down food in the gastrointestinal tract. There are three types of digestive enzymes: amylase, protease, and lipase, which break down carbohydrates, proteins, and fat respectively. Supplemental enzymes can be taken to enhance digestive function. There are three forms of enzyme: plants, microbial (or fungal), and animal enzymes. The most common type of plant enzymes are bromelain from pineapple stems, and papain, from unripe papayas. Both of these help with protein digestion. Microbial enzymes are derived from the fermentation of fungus to break down protein, fats, and carbohydrates. Animal enzymes are derived from animal organs. For example, pancreatic enzymes are derived from the pancreas of either sheep or pig.

Clinically relevant conditions:
  1. Acne
  2. Allergies and food sensitivities
  3. Arthritis and sports injuries (protease enzymes between meals)
  4. Appetite loss
  5. Autoimmune disease
  6. Bad Breath
  7. Digestive disorders (constipation, flatulence, gallstones, gastritis, heartburn, indigestive, digestive candidiasis, nausea, peptic ulcer, stomach cramps, ulcerative colitis)
Food Sources:
Enzymes can be found in many different foods: avocados, papayas, pineapples, apples, bananas, mangoes. Unripe papaya and pineapple are the richest sources. Bitter greens, such are dandelion, kale, collard and mustard are also high in enzymes.

Risk factors and symptoms of deficiency: (who is likely deficient)
A common sign of low digestive function includes bloating and abdominal gas 1-2 hours after meals and stools that float.

Recommended dosage: (how much usually taken)
Consult with your healthcare practitioner. Take 1 to 2 capsules for general digestive support.

Contraindications:(side effects / precautions / interactions / drug interactions)
Side effects are uncommon. Protease enzymes may aggravate those with an active ulcer or gastritis. Check with your doctor if you are taking blood-thinning medication before taking enzymes. Enzymes require coenzymes such as B complex vitamins, vitamin C, vitamin E, and zinc for optimum function. Individuals with candidiasis may experience symptoms of yeast die-off, such as nausea, diarrhea, and bloating when starting to take enzymes.



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